nef gene造句

• The man's virus lacked a functioning nef gene.
• It's not the first study to suggest the nef gene plays an important part in HIV infection.
• Eventually, tests showed that one of HIV's nine genes, the nef gene, was defective in the strain identified in the cluster.
• The simian findings shed new light on the nef gene, which scientists thought was responsible for the virulence of the virus.
• A similar strain of virus, lacking the so-called nef gene, had earlier been given to monkeys in an experiment directed by Desrosiers.
• While these serendipitous discoveries suggest HIV without a nef gene does not trigger AIDS, intentionally infecting people to prove the point is another matter entirely.
• Desrosiers analyzed their viruses and found that one's HIV was indeed missing part of its nef gene _ just like the virus he crafted for the monkey experiment.
• This role of the nef gene was reported by Dr . Didier Trono of the Salk Institute and his colleagues in the January issue of the journal Immunity.
• For unknown reasons, the Australian HIV strain had been weakened by a natural deletion of the nef gene, and it was an obvious candidate for a human vaccine.
• Experiments on primates have shown that a live virus vaccine made by artificially removing the nef gene in the laboratory has achieved the best protection in monkeys against simian AIDS.
• Dr . Ruprecht said in an interview that her research has taught that deletion of the nef gene is not safe for a vaccine because it can still produce disease.
• The Australian virus has three small segments of genetic material that are missing from its nef gene, and two that are absent from a genetic segment known as the long terminal repeat.
• The Nef gene produces a protein in the core of the virus that helps regulate viral activity, while the Gag gene creates a coating around all the genetic material inside the virus.
• In the United States, an experimental vaccine made by deleting the nef gene from a simian AIDS virus provided strong evidence of protection against an AIDS-like virus in early tests in monkeys.
• But he also said the nef gene is known to do several other things that might also promote continued infection, such as increasing the infective potential of fresh virus that leaves an infected cell.